Activity record

PGDB_A047495

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki < 0.5 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS001592
PatentCN116457344A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000067
Compound IDPGDB_C000067
Compound22;22;22;22;22;22;22;22;22
Source record IDPGDB_C000067
InChIKeyXLFRJDTZWHZGJQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001592
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDCN116457344A
Compound location

22;22;22;22;22;22;22;22;22

22;22;22;22;22;22;22;22;22 enlarged structure22;22;22;22;22;22;22;22;22 location on patent page 11
Activity table
Page 87 · table start
Page 88 · table middle
Page 89 · table end