Activity record

PGDB_A047679

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.029 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008051
Compound IDPGDB_C008051
Compound121;121;121
Source record IDPGDB_C008051
InChIKeyVCJJSJVBQYWROI-DETIRCLXSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

121;121;121

121;121;121 enlarged structure121;121;121 location on patent page 41
Activity table
Page 529 · table start
Page 530 · table middle
Page 531 · table middle
Page 532 · table end