Activity record

PGDB_A048086

Assay: % DegradationTarget: CDK2QC: ambiguous
Activity overview

DC50 = 181.5 nM

TargetCDK2
Cell lineHEK293
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001688
PatentWO2025090727A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010138
Compound IDPGDB_C010138
Compound5;5;5;5;5;5;5;5;5
Source record IDPGDB_C010138
InChIKeyBFXCITLRIAUJBZ-JYXGGTNWSA-N

Assay context

Assay IDPGDB_AS001688
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetCDK2
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025090727A1
Compound location

5;5;5;5;5;5;5;5;5

5;5;5;5;5;5;5;5;5 enlarged structure5;5;5;5;5;5;5;5;5 location on patent page 3
Activity table
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