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Compound
PGDB_C010138
5 activity records3 related patents
2D structure
C[C@@H]1[C@@H](Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 63.5 | % | - | 24 h | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A010417 | PGDB_C010138 | PGDB_AS002016 | View |
| Ki | - | <= | 0.1 | uM | - | — | CRBN | CRBN | - | WO2025224262A1 | PGDB_A031199 | PGDB_C010138 | PGDB_AS001844 | View |
| Dmax | - | = | 19.6 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025090727A1 | PGDB_A044198 | PGDB_C010138 | PGDB_AS001842 | View |
| DC50 | - | = | 181.5 | nM | - | — | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A048086 | PGDB_C010138 | PGDB_AS001688 | View |
| Ki | - | <= | 0.1 | uM | - | — | - | - | - | WO2024092039 | PGDB_A058023 | PGDB_C010138 | PGDB_AS001899 | View |