Activity record

PGDB_A048362

Assay: viabilityTarget: PDE3AQC: standardized
Activity overview

IC50 = 2.3 nM

TargetPDE3A
Cell lineSK-MEL-3
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000487
PatentCN118420559B
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006832
Compound IDPGDB_C006832
Compound8;实施例 8;实施例8
Source record IDPGDB_C006832
InChIKeyJNTJTCXFIXNXDV-VNBPQMKGSA-N

Assay context

Assay IDPGDB_AS000487
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
Detection targetcell_proliferation
TargetPDE3A
E3Not specified
Cell lineSK-MEL-3

Source evidence

Patent IDCN118420559B
Compound location

8;实施例 8;实施例8

8;实施例 8;实施例8 enlarged structure8;实施例 8;实施例8 location on patent page 28
Activity table
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