Activity record

PGDB_A048381

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 >= 1000 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002114
PatentWO2024222918A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003267
Compound IDPGDB_C003267
Compound化合物D-1
Source record IDPGDB_C003267
InChIKeyNDSIFXOYXZIPKW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002114
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024222918A1
Compound location

化合物D-1

化合物D-1 enlarged structure化合物D-1 location on patent page 49
Activity table
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