Activity record

PGDB_A049228

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 50-75 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002165
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020197
Compound IDPGDB_C020197
Compound24
Source record IDPGDB_C016327
InChIKeyNLLHQRMLIQLMKY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002165
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

24

24 enlarged structure24 location on patent page 77
Activity table
Page 416 · table start
Page 417 · table middle
Page 418 · table end