Activity record

PGDB_A049417

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 66 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000677
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007983
Compound IDPGDB_C007983
Compound78;78
Source record IDPGDB_C007983
InChIKeyIXAVNWOUPYLGEX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000677
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

78;78

78;78 enlarged structure78;78 location on patent page 24
Activity table
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