Activity record

PGDB_A049598

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki <= 1 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002364
PatentWO2022146151A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009612
Compound IDPGDB_C009612
Compound{280}
Source record IDPGDB_C009612
InChIKeyMULNXVNSFLFRNC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002364
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDWO2022146151A1
Activity table
Page 81 · table start
Page 82 · table middle
Page 83 · table middle
Page 84 · table end