Activity record

PGDB_A049730

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.5-1 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001897
PatentWO2025016359A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019371
Compound IDPGDB_C019371
CompoundGT-05101
Source record IDPGDB_C019371
InChIKeyHUZAGOOSOPGBGC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001897
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-05101

GT-05101 enlarged structureGT-05101 location on patent page 34
Activity table
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Page 215 · table middle
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