Activity record

PGDB_A049811

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 2.2 nM

TargetIKZF2
Time13 d
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000973
PatentCN121487946A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000973
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121487946A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 69
Activity table
Page 76 · table single