Activity record

PGDB_A051215

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.087 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008087
Compound IDPGDB_C008087
Compound157;157;157
Source record IDPGDB_C008087
InChIKeyGBGGESZLVWKUDD-MRJYIUEKSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

157;157;157

157;157;157 enlarged structure157;157;157 location on patent page 45
Activity table
Page 529 · table start
Page 530 · table middle
Page 531 · table middle
Page 532 · table end