Activity record

PGDB_A051623

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 0.5-1 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS001592
PatentCN116457344A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000051
Compound IDPGDB_C000051
Compound7;7;7;7;7
Source record IDPGDB_C000051
InChIKeyWTCOWVCGUAGVKM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001592
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDCN116457344A
Compound location

7;7;7;7;7

7;7;7;7;7 enlarged structure7;7;7;7;7 location on patent page 10
Activity table
Page 87 · table start
Page 88 · table middle
Page 89 · table end