Activity record

PGDB_A052422

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 0.5-5 nM

TargetGSPT1
Cell lineHEK293T
Time7 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002143
PatentWO2025162410A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020467
Compound IDPGDB_C020467
Compound3-1-1;3-1-1;3-1-1
Source record IDPGDB_C020467
InChIKeyYRTMQYAQOMJBKN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002143
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time7 d
TargetGSPT1
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2025162410A1
Compound location

3-1-1;3-1-1;3-1-1

3-1-1;3-1-1;3-1-1 enlarged structure3-1-1;3-1-1;3-1-1 location on patent page 28
Activity table
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