Activity record

PGDB_A052986

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1.16 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000095
PatentWO2024032689A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002592
Compound IDPGDB_C002592
CompoundGT-04194
Source record IDPGDB_C002592
InChIKeyVBTBSYPGFZYQAJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000095
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1
Compound location

GT-04194

GT-04194 enlarged structureGT-04194 location on patent page 51
Activity table
Page 248 · table start
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