Assay

PGDB_AS000095

System: biochemicalTarget: CRBN
Assay context summary

Assay context

281 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Activity compounds and values

Activity records

281 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C002686
IC50-=1.57uM-—CRBNCRBN-WO2024032689A1PGDB_A007049PGDB_C002686PGDB_AS000095View
2D structure for PGDB_C002765
IC50-=1.41uM-—CRBNCRBN-WO2024032689A1PGDB_A007148PGDB_C002765PGDB_AS000095View
2D structure for PGDB_C002529
IC50-=0.31uM-—CRBNCRBN-WO2024032689A1PGDB_A007336PGDB_C002529PGDB_AS000095View
2D structure for PGDB_C002737
IC50-=0.2uM-—CRBNCRBN-WO2024032689A1PGDB_A007387PGDB_C002737PGDB_AS000095View
2D structure for PGDB_C002712
IC50-=1.2uM-—CRBNCRBN-WO2024032689A1PGDB_A007699PGDB_C002712PGDB_AS000095View
2D structure for PGDB_C002739
IC50-=0.94uM-—CRBNCRBN-WO2024032689A1PGDB_A007902PGDB_C002739PGDB_AS000095View
2D structure for PGDB_C002725
IC50-=1.1uM-—CRBNCRBN-WO2024032689A1PGDB_A008319PGDB_C002725PGDB_AS000095View
2D structure for PGDB_C002579
IC50-=0.88uM-—CRBNCRBN-WO2024032689A1PGDB_A008871PGDB_C002579PGDB_AS000095View
2D structure for PGDB_C002655
IC50-=1.26uM-—CRBNCRBN-WO2024032689A1PGDB_A009116PGDB_C002655PGDB_AS000095View
2D structure for PGDB_C002726
IC50-=0.91uM-—CRBNCRBN-WO2024032689A1PGDB_A009368PGDB_C002726PGDB_AS000095View
2D structure for PGDB_C002747
IC50-=0.96uM-—CRBNCRBN-WO2024032689A1PGDB_A009571PGDB_C002747PGDB_AS000095View
2D structure for PGDB_C002701
IC50-=1.01uM-—CRBNCRBN-WO2024032689A1PGDB_A009781PGDB_C002701PGDB_AS000095View
2D structure for PGDB_C002532
IC50-=0.56uM-—CRBNCRBN-WO2024032689A1PGDB_A009918PGDB_C002532PGDB_AS000095View
2D structure for PGDB_C002632
IC50-=0.12uM-—CRBNCRBN-WO2024032689A1PGDB_A010075PGDB_C002632PGDB_AS000095View
2D structure for PGDB_C002662
IC50-=0.11uM-—CRBNCRBN-WO2024032689A1PGDB_A010250PGDB_C002662PGDB_AS000095View
2D structure for PGDB_C002650
IC50-=0.52uM-—CRBNCRBN-WO2024032689A1PGDB_A010465PGDB_C002650PGDB_AS000095View
2D structure for PGDB_C002704
IC50-=0.35uM-—CRBNCRBN-WO2024032689A1PGDB_A010619PGDB_C002704PGDB_AS000095View
2D structure for PGDB_C002555
IC50-=0.7uM-—CRBNCRBN-WO2024032689A1PGDB_A010900PGDB_C002555PGDB_AS000095View
2D structure for PGDB_C002541
IC50-=0.94uM-—CRBNCRBN-WO2024032689A1PGDB_A011340PGDB_C002541PGDB_AS000095View
2D structure for PGDB_C002516
IC50-=0.68uM-—CRBNCRBN-WO2024032689A1PGDB_A012111PGDB_C002516PGDB_AS000095View
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