Activity record

PGDB_A053278

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 > 1100 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001297
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001726
Compound IDPGDB_C001726
Compound4
Source record IDPGDB_C001725
InChIKeyANJMBVHQRLAKBG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001297
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219412A1
Compound location

4

4 enlarged structure4 location on patent page 110
Activity table
Page 167 · table start
Page 168 · table end