Activity record

PGDB_A053431

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001130
PatentUS12540127B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009052
Compound IDPGDB_C009052
CompoundI-75;I-75;I-75
Source record IDPGDB_C009052
InChIKeyJKRDNSLHPRUYBC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001130
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12540127B2
Compound location

I-75;I-75;I-75

I-75;I-75;I-75 enlarged structureI-75;I-75;I-75 location on patent page 58
Activity table
Page 175 · table single