Activity record

PGDB_A053432

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 8.5 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002388
PatentUS12110292B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008988
Compound IDPGDB_C008988
Compound1;1;1;1
Source record IDPGDB_C008988
InChIKeyPYGHGYXMTJJEGF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002388
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12110292B2
Compound location

1;1;1;1

1;1;1;1 enlarged structure1;1;1;1 location on patent page 26
Activity table
Page 102 · table start
Page 103 · table end