Activity record

PGDB_A053474

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

Dmax = 1.7 %

TargetGSPT1
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS000429
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007970
Compound IDPGDB_C007970
Compound65;65
Source record IDPGDB_C007970
InChIKeyQPYMPXOJCVZOQM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000429
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Concentration10 uM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

65;65

65;65 enlarged structure65;65 location on patent page 23
Activity table
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