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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A053593

Assay: % DegradationTarget: IKZF1QC: standardized

Activity overview

degradation = 66 %

TargetIKZF1

Cell lineH929

Concentration10 uM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS001613

PatentCN116457344A

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C019024

CompoundLenalidomide

Source record IDPGDB_C000057

InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001613

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration10 uM

Treatment time24 h

TargetIKZF1

E3Not specified

Cell lineH929

Source evidence

Patent IDCN116457344A

Compound location

Lenalidomide

Lenalidomide enlarged structure

Lenalidomide location on patent page 85

Activity table

Page 93 · table start

Page 94 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU