Activity record

PGDB_A053696

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 3.6 nM

TargetGSPT1
Cell lineHNT-34
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000001
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005302
Compound IDPGDB_C005302
Compound4-136;4-136
Source record IDPGDB_C005302
InChIKeyMGQQVMPHWWNQMF-IAXKEJLGSA-N

Assay context

Assay IDPGDB_AS000001
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHNT-34

Source evidence

Patent IDWO2023078410A1
Compound location

4-136;4-136

4-136;4-136 enlarged structure4-136;4-136 location on patent page 20
Activity table
Page 92 · table start
Page 93 · table end