Activity record

PGDB_A053946

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

EC50 = 0.025 uM

TargetCRBN
E3 ligaseCRBN
Cell lineHEK293T
Time24 h
Assay / ReadoutEC50 / binding
Assay IDPGDB_AS001696
PatentCN117836288A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000417
Compound IDPGDB_C000417
Compound69
Source record IDPGDB_C000417
InChIKeyADTJOHKRUYWZNE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001696
Assay familybinding
Assay systemcell_based
ReadoutEC50
Treatment time24 h
TargetCRBN
E3CRBN
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDCN117836288A
Compound location

69

69 enlarged structure69 location on patent page 48
Activity table
Page 160 · table start
Page 161 · table middle
Page 162 · table end