Assay

PGDB_AS001696

System: cell_basedTarget: CRBNCell line: HEK293T
Assay context summary

Assay context

99 activity records
Assay familybinding
Systemcell_based
ReadoutEC50
TargetCRBN
E3CRBN
Cell lineHEK293T
OrganismHomo sapiens
Activity compounds and values

Activity records

99 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000438
EC50->10uM-—CRBNCRBNHEK293TCN117836288APGDB_A006999PGDB_C000438PGDB_AS001696View
2D structure for PGDB_C000391
EC50-=0.031uM-—CRBNCRBNHEK293TCN117836288APGDB_A007205PGDB_C000391PGDB_AS001696View
2D structure for PGDB_C000409
EC50-=0.015uM-—CRBNCRBNHEK293TCN117836288APGDB_A007493PGDB_C000409PGDB_AS001696View
2D structure for PGDB_C000392
EC50-=0.025uM-—CRBNCRBNHEK293TCN117836288APGDB_A007929PGDB_C000392PGDB_AS001696View
2D structure for PGDB_C000414
EC50-=0.052uM-—CRBNCRBNHEK293TCN117836288APGDB_A008113PGDB_C000414PGDB_AS001696View
2D structure for PGDB_C000462
EC50-=0.006uM-—CRBNCRBNHEK293TCN117836288APGDB_A008719PGDB_C000462PGDB_AS001696View
2D structure for PGDB_C000403
EC50-=0.089uM-—CRBNCRBNHEK293TCN117836288APGDB_A010815PGDB_C000403PGDB_AS001696View
2D structure for PGDB_C000415
EC50-=0.017uM-—CRBNCRBNHEK293TCN117836288APGDB_A010905PGDB_C000415PGDB_AS001696View
2D structure for PGDB_C000424
EC50->10uM-—CRBNCRBNHEK293TCN117836288APGDB_A011255PGDB_C000424PGDB_AS001696View
2D structure for PGDB_C000392
EC50-=0.025uM-—CRBNCRBNHEK293TCN117836288APGDB_A011391PGDB_C000392PGDB_AS001696View
2D structure for PGDB_C000393
EC50-=0.052uM-—CRBNCRBNHEK293TCN117836288APGDB_A012004PGDB_C000393PGDB_AS001696View
2D structure for PGDB_C000440
EC50->10uM-—CRBNCRBNHEK293TCN117836288APGDB_A012352PGDB_C000440PGDB_AS001696View
2D structure for PGDB_C000412
EC50-=0.015uM-—CRBNCRBNHEK293TCN117836288APGDB_A013227PGDB_C000412PGDB_AS001696View
2D structure for PGDB_C000413
EC50-=0.011uM-—CRBNCRBNHEK293TCN117836288APGDB_A013416PGDB_C000413PGDB_AS001696View
2D structure for PGDB_C000467
EC50-=0.018uM-—CRBNCRBNHEK293TCN117836288APGDB_A013612PGDB_C000467PGDB_AS001696View
2D structure for PGDB_C000470
EC50-=0.011uM-—CRBNCRBNHEK293TCN117836288APGDB_A014293PGDB_C000470PGDB_AS001696View
2D structure for PGDB_C000458
EC50-=0.031uM-—CRBNCRBNHEK293TCN117836288APGDB_A014520PGDB_C000458PGDB_AS001696View
2D structure for PGDB_C000397
EC50-=0.033uM-—CRBNCRBNHEK293TCN117836288APGDB_A015714PGDB_C000397PGDB_AS001696View
2D structure for PGDB_C000396
EC50-=0.042uM-—CRBNCRBNHEK293TCN117836288APGDB_A016590PGDB_C000396PGDB_AS001696View
2D structure for PGDB_C000395
EC50-=0.061uM-—CRBNCRBNHEK293TCN117836288APGDB_A016937PGDB_C000395PGDB_AS001696View
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