Activity record

PGDB_A054030

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 8 nM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001113
PatentCA3286762A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025631
Compound IDPGDB_C025631
CompoundExample 37
Source record IDPGDB_C006126
InChIKeyDMUCIXLYLXFAGV-PMERELPUSA-N

Assay context

Assay IDPGDB_AS001113
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN

Source evidence

Patent IDCA3286762A1
Compound location

Example 37

Example 37 enlarged structureExample 37 location on patent page 82
Activity table
Page 103 · table single