Activity record

PGDB_A055413

Assay: % DegradationTarget: SIRT6QC: ambiguous
Activity overview

degradation = 78.4 %

TargetSIRT6
Cell lineSK-HEP-1
Concentration2 uM
Time36 h
Assay / Readout% Degradation
Assay IDPGDB_AS000778
PatentCN119019370A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001518
Compound IDPGDB_C001518
Compound13b;13b
Source record IDPGDB_C001518
InChIKeyHKAZLZVPGXJYCG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000778
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration2 uM
Treatment time36 h
Detection targetprotein_degradation
TargetSIRT6
E3Not specified
Cell lineSK-HEP-1

Source evidence

Patent IDCN119019370A
Compound location

13b;13b

13b;13b enlarged structure13b;13b location on patent page 5
Activity table
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