Activity record

PGDB_A055540

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 < 10 nM

TargetCCNK
Cell lineHEK293T_Nluc_CCNK-tagged
Time4 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001249
PatentWO2025104236
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010859
Compound IDPGDB_C010859
Compound16;16
Source record IDPGDB_C010859
InChIKeyIXYRTWKQINGALB-JTQLQIEISA-N

Assay context

Assay IDPGDB_AS001249
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time4 h
TargetCCNK
E3Not specified
Cell lineHEK293T_Nluc_CCNK-tagged
OrganismHomo sapiens

Source evidence

Patent IDWO2025104236
Compound location

16;16

16;16 enlarged structure16;16 location on patent page 119
Activity table
Page 163 · table start
Page 164 · table end