Activity record

PGDB_A056863

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 52.4 nM

TargetGSPT1
Cell lineMDA-MB-231
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001716
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001872
Compound IDPGDB_C001872
CompoundWX003
Source record IDPGDB_C001872
InChIKeyOJZLQBQHGNYNFY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001716
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineMDA-MB-231

Source evidence

Patent IDWO2023001028A1
Compound location

WX003

WX003 enlarged structureWX003 location on patent page 16
Activity table
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