Activity record

PGDB_A056881

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

Dmax = 73 %

TargetIKZF4
ConcentrationConcentration context: titrated doses
Time13 d
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS000732
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009144
Compound IDPGDB_C009144
CompoundEXAMPLE 1
Source record IDPGDB_C009144
InChIKeyPKEKMIKJWMHBLO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000732
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time13 d
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 69
Activity table
Page 83 · table single