Activity record

PGDB_A057493

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001130
PatentUS12540127B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009049
Compound IDPGDB_C009049
CompoundI-72
Source record IDPGDB_C009049
InChIKeyIKMIKJDOOONTCZ-GHMZBOCLSA-N

Assay context

Assay IDPGDB_AS001130
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12540127B2
Compound location

I-72

I-72 enlarged structureI-72 location on patent page 190
Activity table
Page 175 · table single