Activity record

PGDB_A057655

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 100 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001553
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020437
Compound IDPGDB_C020437
Compound264
Source record IDPGDB_C016567
InChIKeyKITWYRAPQFMWRX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001553
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

264

264 enlarged structure264 location on patent page 87
Activity table
Page 416 · table single