Activity record

PGDB_A057697

Assay: viabilityTarget: PDE3AQC: standardized
Activity overview

IC50 = 6.5 nM

TargetPDE3A
Cell lineSK-MEL-3
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000487
PatentCN118420559B
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006825
Compound IDPGDB_C006825
Compound实施例 265;实施例265
Source record IDPGDB_C006825
InChIKeyYRYSNJRREQGBOS-ZETCQYMHSA-N

Assay context

Assay IDPGDB_AS000487
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
Detection targetcell_proliferation
TargetPDE3A
E3Not specified
Cell lineSK-MEL-3

Source evidence

Patent IDCN118420559B
Compound location

实施例 265;实施例265

实施例 265;实施例265 enlarged structure实施例 265;实施例265 location on patent page 28
Activity table
Page 26 · table single