Activity record

PGDB_A057752

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

Dmax = 1.2 %

TargetGSPT1
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS000429
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008009
Compound IDPGDB_C008009
Compound105;105;105
Source record IDPGDB_C008009
InChIKeyJRZNWCFDDGUKFR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000429
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Concentration10 uM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

105;105;105

105;105;105 enlarged structure105;105;105 location on patent page 27
Activity table
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