Activity record

PGDB_A057954

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 94 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002224
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020440
Compound IDPGDB_C020440
Compound267
Source record IDPGDB_C016570
InChIKeyOYWACFFEUOIJJS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002224
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

267

267 enlarged structure267 location on patent page 87
Activity table
Page 416 · table single