Activity record

PGDB_A058550

Assay: % DegradationTarget: BRAFQC: standardized
Activity overview

Emax = 10.83 %

TargetBRAF
Cell lineA375.10
Concentration10 uM
Time24 h
Assay / Readoutluminescence / Emax
Assay IDPGDB_AS001074
PatentAU2022290851A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005755
Compound IDPGDB_C005755
CompoundExample 103
Source record IDPGDB_C005755
InChIKeyJOXVKSKPHOECKA-BAKTURSRSA-N

Assay context

Assay IDPGDB_AS001074
Assay family% Degradation
Assay systemcell_based
ReadoutEmax
Technologyluminescence
Concentration10 uM
Treatment time24 h
TargetBRAF
E3Not specified
Cell lineA375.10

Source evidence

Patent IDAU2022290851A1
Compound location

Example 103

Example 103 enlarged structureExample 103 location on patent page 523
Activity table
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