Assay

PGDB_AS001074

System: cell_basedTarget: BRAFCell line: A375.10
Assay context summary

Assay context

58 activity records
Assay family% Degradation
Systemcell_based
ReadoutEmax
TargetBRAF
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

58 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005776
Emax-=12.02%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A007112PGDB_C005776PGDB_AS001074View
2D structure for PGDB_C005756
Emax-=22.27%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A008093PGDB_C005756PGDB_AS001074View
2D structure for PGDB_C005759
Emax-=9.8%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A009541PGDB_C005759PGDB_AS001074View
2D structure for PGDB_C005793
Emax-=23%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A009779PGDB_C005793PGDB_AS001074View
2D structure for PGDB_C005782
Emax-=7.25%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A010181PGDB_C005782PGDB_AS001074View
2D structure for PGDB_C005740
Emax-=10.07%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A010573PGDB_C005740PGDB_AS001074View
2D structure for PGDB_C005777
Emax-=12.58%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A010902PGDB_C005777PGDB_AS001074View
2D structure for PGDB_C005757
Emax-=11.78%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A014142PGDB_C005757PGDB_AS001074View
2D structure for PGDB_C005774
Emax-=8.26%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A014631PGDB_C005774PGDB_AS001074View
2D structure for PGDB_C005765
Emax-=11.1%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A015168PGDB_C005765PGDB_AS001074View
2D structure for PGDB_C005763
Emax-=10.27%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A017638PGDB_C005763PGDB_AS001074View
2D structure for PGDB_C005771
Emax-=12.8%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A018113PGDB_C005771PGDB_AS001074View
2D structure for PGDB_C005788
Emax-=25.09%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A019687PGDB_C005788PGDB_AS001074View
2D structure for PGDB_C005749
Emax-=8.43%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A019942PGDB_C005749PGDB_AS001074View
2D structure for PGDB_C005783
Emax-=8.05%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A019970PGDB_C005783PGDB_AS001074View
2D structure for PGDB_C005758
Emax-=16.71%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A021291PGDB_C005758PGDB_AS001074View
2D structure for PGDB_C005783
Emax-=8.5%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A025852PGDB_C005783PGDB_AS001074View
2D structure for PGDB_C005770
Emax-=9.98%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A026755PGDB_C005770PGDB_AS001074View
2D structure for PGDB_C005745
Emax-=7.37%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A027007PGDB_C005745PGDB_AS001074View
2D structure for PGDB_C005766
Emax-=9.6%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A027960PGDB_C005766PGDB_AS001074View
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