Activity record

PGDB_A058713

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 28.26 nM

TargetCDK12
Cell lineMDA-MB-468
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000556
PatentCN121108130A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007328
Compound IDPGDB_C007328
Compound实施例5
Source record IDPGDB_C007328
InChIKeyWCBPFMWVFSSNBW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000556
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified
Cell lineMDA-MB-468

Source evidence

Patent IDCN121108130A
Compound location

实施例5

实施例5 enlarged structure实施例5 location on patent page 23
Activity table
Page 36 · table single