Activity record

PGDB_A058975

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 0.23 uM

TargetCRBN
E3 ligaseCRBN
Time30 min
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS001033
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020445
Compound IDPGDB_C020445
Compound272
Source record IDPGDB_C020445
InChIKeySWVJPMBPKVLTAJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001033
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
Treatment time30 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDWO2025024521A1
Activity table
Page 414 · table start
Page 415 · table middle
Page 416 · table end