Activity record

PGDB_A058981

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 1-10 nM

TargetGSPT1
Cell lineMOLM-13
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000118
PatentWO2024222918A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003265
Compound IDPGDB_C003265
Compound化合物B-4
Source record IDPGDB_C003265
InChIKeyMJPLTGIITXCPSU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000118
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineMOLM-13

Source evidence

Patent IDWO2024222918A1
Compound location

化合物B-4

化合物B-4 enlarged structure化合物B-4 location on patent page 48
Activity table
Page 53 · table single