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Compound
PGDB_C003265
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CNC(=O)C4COc5ccc(OC(F)(F)F)cc5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 1 | nM | - | — | GSPT1 | - | MV-4-11 | WO2024222918A1 | PGDB_A021085 | PGDB_C003265 | PGDB_AS001375 | View |
| IC50 | - | < | 1 | nM | - | — | GSPT1 | - | KG-1 | WO2024222918A1 | PGDB_A024929 | PGDB_C003265 | PGDB_AS002114 | View |
| IC50 | - | = | 1-10 | nM | - | — | GSPT1 | - | MOLM-13 | WO2024222918A1 | PGDB_A058981 | PGDB_C003265 | PGDB_AS000118 | View |
| IC50 | - | = | 1-10 | nM | - | — | GSPT1 | - | U937 | WO2024222918A1 | PGDB_A076929 | PGDB_C003265 | PGDB_AS002362 | View |
| % Degradation | - | >= | 80 | % | 200 nM | 4 h | GSPT1 | - | KG-1 | WO2024222918A1 | PGDB_A077192 | PGDB_C003265 | PGDB_AS000482 | View |