Activity record

PGDB_A058985

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.75 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000095
PatentWO2024032689A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002560
Compound IDPGDB_C002560
CompoundGT-05683
Source record IDPGDB_C002560
InChIKeyJHWWCEAZUIBANQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000095
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1
Compound location

GT-05683

GT-05683 enlarged structureGT-05683 location on patent page 52
Activity table
Page 248 · table start
Page 249 · table middle
Page 250 · table end