Activity record

PGDB_A060495

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 4.84 nM

TargetGSPT1
Cell lineHEK293
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001853
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001466
Compound IDPGDB_C001466
Compound实施例16
Source record IDPGDB_C001466
InChIKeyYXPYUSWLMCNTDN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001853
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDCN118852145A
Compound location

实施例16

实施例16 enlarged structure实施例16 location on patent page 48
Activity table
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