Activity record

PGDB_A061296

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 8.3 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002388
PatentUS12110292B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008999
Compound IDPGDB_C008999
Compound13
Source record IDPGDB_C008999
InChIKeyJUCGWWSMSDVSHT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002388
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12110292B2
Compound location

13

13 enlarged structure13 location on patent page 63
Activity table
Page 102 · table start
Page 103 · table end