Activity record

PGDB_A061645

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 76 %

TargetIKZF1
ConcentrationConcentration context: titrated doses
Time24 h
Assay / Readoutflow_cytometry / % Degradation
Assay IDPGDB_AS000316
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010125
Compound IDPGDB_C010125
CompoundEXAMPLE 1
Source record IDPGDB_C010125
InChIKeyZMLKQUYYZBYSNQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000316
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time24 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 81
Activity table
Page 110 · table single