Activity record

PGDB_A062002

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 100-1000 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000307
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011607
Compound IDPGDB_C011607
CompoundExample 20
Source record IDPGDB_C011607
InChIKeyVXIGKWNRRPVTME-HZOUACISSA-N

Assay context

Assay IDPGDB_AS000307
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 20

Example 20 enlarged structureExample 20 location on patent page 58
Activity table
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