Activity record

PGDB_A063285

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 3.66 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000788
PatentWO2023151635A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001165
Compound IDPGDB_C001165
CompoundGT-02598
Source record IDPGDB_C001165
InChIKeyPWLHTQLSYWAPMZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000788
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2023151635A1
Compound location

GT-02598

GT-02598 enlarged structureGT-02598 location on patent page 268
Activity table
Page 358 · table single