Activity record

PGDB_A063362

Assay: biochemicalTarget: CTNNB1QC: ambiguous
Activity overview

EC50 < 1 uM

TargetCTNNB1
E3 ligaseBTRC | FBXW11
Time1 h
Assay / ReadoutEC50 / biochemical
Assay IDPGDB_AS000640
PatentWO2025179005A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C021134
Compound IDPGDB_C021134
Compound188
Source record IDPGDB_C021129
InChIKeyHDBBPCZJPOCKSH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000640
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
Treatment time1 h
TargetBTRC | FBXW11 | SKP1
E3BTRC | FBXW11 | SKP1

Source evidence

Patent IDWO2025179005A1
Compound location

188

188 enlarged structure188 location on patent page 442
Activity table
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