Activity record

PGDB_A063428

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

DC50 = 4 nM

TargetIKZF4
Time13 d
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001336
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010128
Compound IDPGDB_C010128
CompoundEXAMPLE 4
Source record IDPGDB_C010128
InChIKeySQGFGLKDMPXDDJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001336
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

EXAMPLE 4

EXAMPLE 4 enlarged structureEXAMPLE 4 location on patent page 93
Activity table
Page 109 · table single