Activity record

PGDB_A063696

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 > 10000 nM

TargetGSPT1
Cell lineJURKAT.21
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001042
PatentAU2021361043A9
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C016640
Compound IDPGDB_C016640
Compound128;128;128
Source record IDPGDB_C016640
InChIKeyKCANMRJIENRROH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001042
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetIKZF2
E3Not specified
Cell lineJURKAT.21

Source evidence

Patent IDAU2021361043A9
Compound location

128;128;128

128;128;128 enlarged structure128;128;128 location on patent page 279
Activity table
Page 295 · table single