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Compound
PGDB_C016640
10 activity records2 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(C4CCN(Cc5cccc(S(=O)(=O)N6CCOCC6)c5)CC4)c4nccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 60-95 | % | - | - | IKZF2 | - | - | AU2021361043A9 | PGDB_A009186 | PGDB_C016640 | PGDB_AS000275 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A014162 | PGDB_C016640 | PGDB_AS001296 | View |
| Emax | - | > | 95 | % | - | - | IKZF2 | - | - | AU2021361043A9 | PGDB_A014355 | PGDB_C016640 | PGDB_AS000347 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A023965 | PGDB_C016640 | PGDB_AS000287 | View |
| DC50 | - | > | 100 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A024869 | PGDB_C016640 | PGDB_AS001223 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A045991 | PGDB_C016640 | PGDB_AS001913 | View |
| DC50 | - | = | 500-10000 | nM | - | — | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A058131 | PGDB_C016640 | PGDB_AS000070 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A062826 | PGDB_C016640 | PGDB_AS000499 | View |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | JURKAT.21 | AU2021361043A9 | PGDB_A063696 | PGDB_C016640 | PGDB_AS001042 | View |
| DC50 | - | = | 500-10000 | nM | - | — | GSPT1 | - | JURKAT.21 | AU2021361043A9 | PGDB_A073275 | PGDB_C016640 | PGDB_AS001854 | View |